CHARLES RIVER LABS

Experience Charles River Laboratories

A position of responsibility

Bringing and sustaining vital drugs to market safely, and as quickly as possible.

Signatory of United Nations Global Compact (UNGC)

Renewable electricity goal reached in 2024

See how our purpose-driven Environmental, Social and Governance (ESG) strategies empower and drive us.

people enrolled in Employee Resource Groups (ERGs)

of our total leadership in 2023 are women

We strive for a culture where our employees are connected to our purpose, provided with a breadth of career opportunities, and can bring their authentic selves to work.

awarded by the Foundation for Chemistry Research and Initiatives (FCRI) toward a multidisciplinary program with MatTek Corporation to develop a New Approach Methodology (NAM) inhalation toxicology test

IND submissions containing Retrogenix® platform data supported across multiple regulatory bodies (FDA, EMA, and PMDA)

Learn about our dedication to the pursuit of scientific and technological innovation to develop alternatives to animals in testing.

Of the FDA-approved drugs over the past five years were worked on by Charles River

IND studies supported in the last 12 months

Listen to the stories behind the bold science from those developing and receiving life-changing therapies.

Non-Viral Engineering of T Cells

Advancing Therapeutic Delivery in CNS Diseases

Synthetic DNA Library of Animal Proteins an Industry First

NGS-Based Viral Safety Testing for ATMPs: Mandatory or Just an Option?

Finding the Cure for Childhood Cancer and Rare Diseases

Dec 12, 2024 | Webinar

Re-examining DART Dose Level Selection for ECHA Submissions

Dec 15 - 18, 2024 | San Diego, CA | Conference

Antibody Engineering & Therapeutics

Jan 20 - 23, 2025 | Dallas, TX | Booth #235 | Conference

Advanced Therapies Week 2025

Jan 25 - 29, 2025 | San Diego, CA | Conference

SLAS2025 International Conference & Exhibition

Mar 25 - 27, 2025 | Charleston, SC | Symposium

QC Micro Summit 2025

No matter where you are in your drug development journey, we can provide you with a wide range of products, models, services and guidance that are tailored to your specific needs.

Research Models and Services

Support your basic research with help from the leading global supplier of laboratory animal models and services.

Human Immune and Stem Cells

The leading developers of cutting-edge cell therapies and basic research trust us as their cell sourcing provider.

Genetically Engineered Animals and Services

Genetically Engineered Animal Models and Services (GEMS) team helps you select, customize, and maintain the right mice for your research. Services for genetically engineered animals include mouse and rat model creation, breeding, genotyping, and mouse embryo and sperm cryopreservation.

Integrated Drug Discovery

Reduce time to clinic by up to a year with an integrated drug discovery approach in which target discovery, hit id, hit-to-lead, lead optimization, safety, and toxicology are all managed by the same project team.

Discovery Pharmacology Studies

In vitro to in vivo translation is difficult, costly, and often fails. Advance your discovery research with our translationally focused approach across a range of therapeutic areas including oncology, neuroscience, and immunology.

Antibody Discovery Services

Antibody discovery services designed with your IND in mind. Comprehensive solutions, tailored to your unique vision for your next antibody therapeutic.

Non-GLP Integrated Toxicology

Two primary study offerings are available for non-GLP toxicology studies for lead optimization and preclinical development.

IND-enabling Programs

Successfully initiate and complete your IND-enabling program while meeting regulatory expectations with our unique range of IND-enabling studies.

Carcinogenicity Studies

Our carcinogenicity studies include expert support in project design, model selection, and in vivo and ex vivo data for final submission.

Biologics Testing Solutions

Our tailored global testing and manufacturing services support clients throughout the biologic development cycle, from discovery through preclinical and clinical studies to marketed product release.

Biologics Contract Manufacturing

Accelerate the development of your biopharmaceutical from concept to cure with our CGMP compliant biologics contract manufacturing services. 

Rightsource^SM – Biologics Insourcing Solutions

A flexible testing platform that can be deployed where and when you need it, whether it’s located at your facility, one of our satellite labs, or even within the walls of the many Charles River facilities itself.

Cell and Gene CDMO Solutions

Fastrack your cell and gene development and manufacturing with our end-to-end scalable solutions from early stage-research and testing through commercial release.

Biologics Testing and Manufacturing Solutions

Navigate seamlessly throughout the biologic development cycle, from early concept to market-ready with our tailored, CGMP global testing and manufacturing solutions.

Microbiology Quality Control Solutions

Elevate your contamination control strategy and accelerate production with confidence. Our rapid, accurate, and compliant microbial testing solutions optimize your QC workflow.

One Step Manufacturing

One Step by Charles River is a comprehensive, tailored suite of CRO drug discovery and development services in target discovery, lead optimization, development chemistry, GMP, drug product development and CMC strategy.

Expedite your investigational new drug (IND) application with Fast Lane Paradigm. Learn how to reduce white space between studies and accelerate time to clinic for you INDs.